Symbol
Name
ID

Sec23b
SEC23 homolog B, COPII coat complex component
MGI:1350925

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Goiter	Papillary thyroid carcinoma	Hashimoto thyroiditis
Disease(s) Associated with SEC23B
Cowden syndrome 7

Mouse Phenotypes

nasal gland degeneration

abnormal pancreatic acinus morphology

abnormal pancreatic acinar cell morphology

absent pancreatic acinar cell zymogen granule

decreased pancreatic acinar cell number

pancreatic acinar hypoplasia

abnormal Paneth cell morphology

abnormal salivary gland morphology

abnormal sublingual gland morphology

abnormal submandibular gland morphology

salivary gland degeneration

gastric gland degeneration

abnormal exocrine pancreas physiology

abnormal endocrine pancreas morphology

decreased pancreatic alpha cell number

decreased pancreatic beta cell number

decreased pancreatic islet number

abnormal endocrine pancreas development

abnormal pancreas morphology

small pancreas

pancreas degeneration

pancreas inflammation

Availability

Mouse Genotype

Sec23b^{Gt(AD0407)Wtsi}/Sec23b^{Gt(AD0407)Wtsi}

Sec23b^{tm1a(EUCOMM)Wtsi}/Sec23b^{tm1a(EUCOMM)Wtsi}

Sec23b^{tm1b(EUCOMM)Wtsi}/Sec23b^{tm1b(EUCOMM)Wtsi}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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